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VIP (Vasoactive Intestinal Peptide)

VIP (Vasoactive Intestinal Peptide) is a naturally occurring 28-amino-acid neuropeptide encoded by the VIP gene in humans. It belongs to the glucagon/secretin peptide superfamily and acts as a ligand for two class-II G-protein-coupled receptors: VPAC1 and VPAC2. Synthetic VIP is supplied for laboratory studies on receptor signaling.

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Product Specifications

  • Sequence: 28 amino acids
  • Family: Glucagon/secretin superfamily
  • Receptors: VPAC1 / VPAC2
  • Format: 5mg x 30 tablets
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Research use only. Not for human or animal use.

Research Summary

  • VIP binds VPAC1 and VPAC2, activating G-alpha signaling that elevates cyclic AMP and activates protein kinase A.
  • Naturally produced in the gut, pancreas, neocortex, suprachiasmatic nuclei, and immune cells.
  • Research has examined VIP in cardiovascular signaling, smooth-muscle relaxation, gastrointestinal regulation, and immunomodulation.
  • Synthetic VIP is used in vitro for analyzing receptor binding and structure-activity research.

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Important Disclaimer

This page is for educational and informational purposes only. This product is a research chemical sold for laboratory use only. Not intended for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider. These statements have not been evaluated by the FDA.