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SLU-PP-332 (Pan-ERR Agonist)

SLU-PP-332 is a synthetic small molecule (C18H14N2O2) studied as a potent pan-ERR (estrogen-related receptor) agonist with primary activity at ERR-alpha (EC50 ~98 nM) and additional activity at ERR-gamma. Despite often being marketed alongside peptides, SLU-PP-332 is not a peptide — it is a small-molecule research compound studied in animal models for exercise-mimetic gene expression.

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Product Specifications

  • Format: 1mg x 60 tablets
  • Class: ERR agonist (small molecule)
  • Target: ERR-alpha / ERR-gamma
  • Documentation available
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Research use only. Not for human or animal use.

Research Summary

  • SLU-PP-332 binds the ligand-binding domain of ERR-alpha, stabilizing its active conformation and enhancing PGC-1-alpha coactivator interactions.
  • Mouse studies have reported increased endurance and altered metabolic gene expression with SLU-PP-332.
  • Effects in research include increased fatty acid oxidation, mitochondrial biogenesis markers, and reduced respiratory exchange ratio.
  • All current data are preclinical — there are no human clinical trials of SLU-PP-332 published as of early 2026.

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Important Disclaimer

This page is for educational and informational purposes only. This product is a research chemical sold for laboratory use only. Not intended for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider. These statements have not been evaluated by the FDA.