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ATX-304 (Pan-AMPK Activator)

ATX-304 is a small-molecule pan-AMPK activator originally developed by Betagenon AB and now in clinical research with Amplifier Therapeutics. It is peripherally restricted (does not cross the blood-brain barrier) and is studied for AMP-activated protein kinase signaling, mitochondrial activity, and metabolic gene expression. Supplied as 100mg x 60 tablets.

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Product Specifications

  • Format: 100mg x 60 tablets
  • Class: Pan-AMPK activator
  • Profile: Peripherally restricted
  • Documentation available
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Research use only. Not for human or animal use.

Research Summary

  • ATX-304 activates AMPK, an enzyme naturally activated by low cellular energy that signals glucose uptake and fatty-acid mobilization.
  • Cell studies in tubular epithelial cells reported a 38% increase in basal oxygen consumption rate with ATX-304.
  • Preclinical animal studies examined effects on fat mass and liver steatosis without altered food intake.
  • Early human clinical trials have evaluated ATX-304 combined with metformin in metabolic research.

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Important Disclaimer

This page is for educational and informational purposes only. This product is a research chemical sold for laboratory use only. Not intended for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider. These statements have not been evaluated by the FDA.